JPL - Blog Posts

5 Ways Studying Water Will Help Us Better Understand Earth

Studying our home planet is just as powerful as exploring what’s beyond it.

Surface Water and Ocean Topography (SWOT) is a joint mission developed by NASA and the French space agency Centre National d’Études Spatiales (CNES), with contributions from the Canadian Space Agency and the UK Space Agency. It will track water on more than 90% of Earth’s surface and help communities, scientists, and researchers better understand this finite and vital resource. And it’s launching this month!

So how will SWOT help us better understand Earth? Here are 5 ways.

SWOT will address some of the most pressing climate change questions of our time.

An important part of predicting our future climate is determining at what point Earth’s ocean water slows down its absorption of the excess heat in the atmosphere and starts releasing that heat back into the air, where it could accelerate global warming. SWOT will provide crucial information about this global heat exchange between the ocean and the atmosphere, enabling researchers to test and improve future climate forecasts.

The satellite will also offer insights to improve computer models for sea level rise projections and coastal flood forecasting.

Data from SWOT will additionally help scientists, engineers, water managers, and others better monitor drought conditions in lakes and reservoirs and improve flood forecasts for rivers.

SWOT is the first satellite mission that will observe nearly all water on the planet’s surface.

SWOT will measure the height of water in Earth’s lakes, rivers, reservoirs, and the ocean, giving scientists the ability to track the movement of water around the world.

SWOT’s eye in the sky will provide a truly global view of the water on more than 90% of Earth’s surface, enriching humankind’s understanding of how the ocean reacts to and influences climate change along with what potential hazards – including floods – lie ahead in different regions of the world.

SWOT will see Earth’s water in higher definition than ever before.

Because everything is better in HD 😉, SWOT will view Earth’s ocean and freshwater bodies with unprecedented clarity compared to other satellites, much like a high-definition television delivers a picture far more detailed than older models. This means that SWOT will be able to “see” ocean features – like fronts and eddies – that are too small for current space-based instruments to detect. Those measurements will help improve researchers’ understanding of the ocean’s role in climate change.

Not only will the satellite show where – and how fast – sea level is rising, it will also reveal how coastlines around the world are changing. It will provide similar high-definition clarity for Earth’s lakes, rivers, and reservoirs, many of which remain a mystery to researchers, who aren’t able to outfit every water body with monitoring instruments.

SWOT data will be used to help make decisions about our daily lives and livelihoods.

As climate change accelerates the water cycle, more communities around the world will be inundated with water while others won’t have enough. SWOT data will be used to monitor drought conditions and improve flood forecasts, providing essential information to water management agencies, disaster preparedness agencies, universities, civil engineers, and others who need to track water in their local areas. SWOT data also will help industries, like shipping, by providing measurements of water levels along rivers, as well as ocean conditions, including tides, currents, and storm surges.

Finally … SWOT will pave the way for future Earth missions.

With its innovative technology and commitment to engaging a diverse community of people who plan to use data from the mission, SWOT is blazing a trail for future Earth-observing missions. SWOT’s data and the tools to support researchers in analyzing the information will be free and accessible. This will help to foster research and applications activities by a wide range of users, including scientists, resource managers, and others who in the past may not have had the opportunity to access this kind of information. Lessons learned from SWOT will lead to new questions and improvements for future missions, including our upcoming Earth System Observatory, a constellation of missions focused on studying key aspects of our home planet.

Keep track of the mission here. And make sure to follow us on Tumblr for your regular dose of space!

For the second time in history, a human-made object has reached the space between the stars. Our Voyager 2 probe now has exited the heliosphere – the protective bubble of particles and magnetic fields created by the Sun.

Comparing data from different instruments aboard the trailblazing spacecraft, mission scientists determined the probe crossed the outer edge of the heliosphere on Nov. 5. This boundary, called the heliopause, is where the tenuous, hot solar wind meets the cold, dense interstellar medium. Its twin, Voyager 1, crossed this boundary in 2012, but Voyager 2 carries a working instrument that will provide first-of-its-kind observations of the nature of this gateway into interstellar space.

Voyager 2 now is slightly more than 11 billion miles (18 billion kilometers) from Earth. Mission operators still can communicate with Voyager 2 as it enters this new phase of its journey, but information – moving at the speed of light – takes about 16.5 hours to travel from the spacecraft to Earth. By comparison, light traveling from the Sun takes about eight minutes to reach Earth.

Read more at https://go.nasa.gov/2QG2s16 or follow along with the mission @NASAVoyager on Twitter.

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Frozen: Ice on Earth and Well Beyond

Icy Hearts: A heart-shaped calving front of a glacier in Greenland (left) and Pluto's frozen plains (right). Credits: NASA/Maria-Jose Viñas and NASA/APL/SwRI

From deep below the soil at Earth’s polar regions to Pluto’s frozen heart, ice exists all over the solar system...and beyond. From right here on our home planet to moons and planets millions of miles away, we’re exploring ice and watching how it changes. Here’s 10 things to know:

1. Earth’s Changing Ice Sheets

An Antarctic ice sheet. Credit: NASA

Ice sheets are massive expanses of ice that stay frozen from year to year and cover more than 6 million square miles. On Earth, ice sheets extend across most of Greenland and Antarctica. These two ice sheets contain more than 99 percent of the planet’s freshwater ice. However, our ice sheets are sensitive to the changing climate.

Data from our GRACE satellites show that the land ice sheets in both Antarctica and Greenland have been losing mass since at least 2002, and the speed at which they’re losing mass is accelerating.

2. Sea Ice at Earth’s Poles

Earth’s polar oceans are covered by stretches of ice that freezes and melts with the seasons and moves with the wind and ocean currents. During the autumn and winter, the sea ice grows until it reaches an annual maximum extent, and then melts back to an annual minimum at the end of summer. Sea ice plays a crucial role in regulating climate – it’s much more reflective than the dark ocean water, reflecting up to 70 percent of sunlight back into space; in contrast, the ocean reflects only about 7 percent of the sunlight that reaches it. Sea ice also acts like an insulating blanket on top of the polar oceans, keeping the polar wintertime oceans warm and the atmosphere cool.

Some Arctic sea ice has survived multiple years of summer melt, but our research indicates there’s less and less of this older ice each year. The maximum and minimum extents are shrinking, too. Summertime sea ice in the Arctic Ocean now routinely covers about 30-40 percent less area than it did in the late 1970s, when near-continuous satellite observations began. These changes in sea ice conditions enhance the rate of warming in the Arctic, already in progress as more sunlight is absorbed by the ocean and more heat is put into the atmosphere from the ocean, all of which may ultimately affect global weather patterns.

3. Snow Cover on Earth

Snow extends the cryosphere from the poles and into more temperate regions.

Snow and ice cover most of Earth’s polar regions throughout the year, but the coverage at lower latitudes depends on the season and elevation. High-elevation landscapes such as the Tibetan Plateau and the Andes and Rocky Mountains maintain some snow cover almost year-round. In the Northern Hemisphere, snow cover is more variable and extensive than in the Southern Hemisphere.

Snow cover the most reflective surface on Earth and works like sea ice to help cool our climate. As it melts with the seasons, it provides drinking water to communities around the planet.

4. Permafrost on Earth

Tundra polygons on Alaska's North Slope. As permafrost thaws, this area is likely to be a source of atmospheric carbon before 2100. Credit: NASA/JPL-Caltech/Charles Miller

Permafrost is soil that stays frozen solid for at least two years in a row. It occurs in the Arctic, Antarctic and high in the mountains, even in some tropical latitudes. The Arctic’s frozen layer of soil can extend more than 200 feet below the surface. It acts like cold storage for dead organic matter – plants and animals.

In parts of the Arctic, permafrost is thawing, which makes the ground wobbly and unstable and can also release those organic materials from their icy storage. As the permafrost thaws, tiny microbes in the soil wake back up and begin digesting these newly accessible organic materials, releasing carbon dioxide and methane, two greenhouse gases, into the atmosphere.

Two campaigns, CARVE and ABoVE, study Arctic permafrost and its potential effects on the climate as it thaws.

5. Glaciers on the Move

Did you know glaciers are constantly moving? The masses of ice act like slow-motion rivers, flowing under their own weight. Glaciers are formed by falling snow that accumulates over time and the slow, steady creep of flowing ice. About 10 percent of land area on Earth is covered with glacial ice, in Greenland, Antarctica and high in mountain ranges; glaciers store much of the world's freshwater.

Our satellites and airplanes have a bird’s eye view of these glaciers and have watched the ice thin and their flows accelerate, dumping more freshwater ice into the ocean, raising sea level.

6. Pluto’s Icy Heart

The nitrogen ice glaciers on Pluto appear to carry an intriguing cargo: numerous, isolated hills that may be fragments of water ice from Pluto's surrounding uplands. NASA/Johns Hopkins University Applied Physics Laboratory/Southwest Research Institute

Pluto’s most famous feature – that heart! – is stone cold. First spotted by our New Horizons spacecraft in 2015, the heart’s western lobe, officially named Sputnik Planitia, is a deep basin containing three kinds of ices – frozen nitrogen, methane and carbon monoxide.

Models of Pluto’s temperatures show that, due the dwarf planet’s extreme tilt (119 degrees compared to Earth’s 23 degrees), over the course of its 248-year orbit, the latitudes near 30 degrees north and south are the coldest places – far colder than the poles. Ice would have naturally formed around these latitudes, including at the center of Sputnik Planitia.

New Horizons also saw strange ice formations resembling giant knife blades. This “bladed terrain” contains structures as tall as skyscrapers and made almost entirely of methane ice, likely formed as erosion wore away their surfaces, leaving dramatic crests and sharp divides. Similar structures can be found in high-altitude snowfields along Earth’s equator, though on a very different scale.

7. Polar Ice on Mars

This image, combining data from two instruments aboard our Mars Global Surveyor, depicts an orbital view of the north polar region of Mars. Credit: NASA/JPL-Caltech/MSSS

Mars has bright polar caps of ice easily visible from telescopes on Earth. A seasonal cover of carbon dioxide ice and snow advances and retreats over the poles during the Martian year, much like snow cover on Earth.

This animation shows a side-by-side comparison of CO2 ice at the north (left) and south (right) Martian poles over the course of a typical year (two Earth years). This simulation isn't based on photos; instead, the data used to create it came from two infrared instruments capable of studying the poles even when they're in complete darkness. This data were collected by our Mars Reconnaissance Orbiter, and Mars Global Surveyor. Credit: NASA/JPL-Caltech

During summertime in the planet's north, the remaining northern polar cap is all water ice; the southern cap is water ice as well, but remains covered by a relatively thin layer of carbon dioxide ice even in summertime.

Scientists using radar data from our Mars Reconnaissance Orbiter found a record of the most recent Martian ice age in the planet's north polar ice cap. Research indicates a glacial period ended there about 400,000 years ago. Understanding seasonal ice behavior on Mars helps scientists refine models of the Red Planet's past and future climate.

8. Ice Feeds a Ring of Saturn

Wispy fingers of bright, icy material reach tens of thousands of kilometers outward from Saturn's moon Enceladus into the E ring, while the moon's active south polar jets continue to fire away. Credit: NASA/JPL/Space Science Institute

Saturn’s rings and many of its moons are composed of mostly water ice – and one of its moons is actually creating a ring. Enceladus, an icy Saturnian moon, is covered in “tiger stripes.” These long cracks at Enceladus’ South Pole are venting its liquid ocean into space and creating a cloud of fine ice particles over the moon's South Pole. Those particles, in turn, form Saturn’s E ring, which spans from about 75,000 miles (120,000 kilometers) to about 260,000 miles (420,000 kilometers) above Saturn's equator. Our Cassini spacecraft discovered this venting process and took high-resolution images of the system.

Jets of icy particles burst from Saturn’s moon Enceladus in this brief movie sequence of four images taken on Nov. 27, 2005. Credit: NASA/JPL/Space Science Institute

9. Ice Rafts on Europa

View of a small region of the thin, disrupted, ice crust in the Conamara region of Jupiter's moon Europa showing the interplay of surface color with ice structures. Credit: NASA/JPL/University of Arizona

The icy surface of Jupiter’s moon Europa is crisscrossed by long fractures. During its flybys of Europa, our Galileo spacecraft observed icy domes and ridges, as well as disrupted terrain including crustal plates that are thought to have broken apart and "rafted" into new positions. An ocean with an estimated depth of 40 to 100 miles (60 to 150 kilometers) is believed to lie below that 10- to 15-mile-thick (15 to 25 km) shell of ice.

The rafts, strange pits and domes suggest that Europa’s surface ice could be slowly turning over due to heat from below. Our Europa Clipper mission, targeted to launch in 2022, will conduct detailed reconnaissance of Europa to see whether the icy moon could harbor conditions suitable for life.

10. Crater Ice on Our Moon

The image shows the distribution of surface ice at the Moon’s south pole (left) and north pole (right), detected by our Moon Mineralogy Mapper instrument. Credit: NASA

In the darkest and coldest parts of our Moon, scientists directly observed definitive evidence of water ice. These ice deposits are patchy and could be ancient. Most of the water ice lies inside the shadows of craters near the poles, where the warmest temperatures never reach above -250 degrees Fahrenheit. Because of the very small tilt of the Moon’s rotation axis, sunlight never reaches these regions.

A team of scientists used data from a our instrument on India’s Chandrayaan-1 spacecraft to identify specific signatures that definitively prove the water ice. The Moon Mineralogy Mapper not only picked up the reflective properties we’d expect from ice, but was able to directly measure the distinctive way its molecules absorb infrared light, so it can differentiate between liquid water or vapor and solid ice.

With enough ice sitting at the surface – within the top few millimeters – water would possibly be accessible as a resource for future expeditions to explore and even stay on the Moon, and potentially easier to access than the water detected beneath the Moon’s surface.

11. Bonus: Icy World Beyond Our Solar System!

With an estimated temperature of just 50K, OGLE-2005-BLG-390L b is the chilliest exoplanet yet discovered. Pictured here is an artist's concept. Credit: NASA

OGLE-2005-BLG-390Lb, the icy exoplanet otherwise known as Hoth, orbits a star more than 20,000 light years away and close to the center of our Milky Way galaxy. It’s locked in the deepest of deep freezes, with a surface temperature estimated at minus 364 degrees Fahrenheit (minus 220 Celsius)!

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What’s Up For September 2018?

Outstanding views Venus, Jupiter, Saturn and Mars with the naked eye!

You'll have to look quickly after sunset to catch Venus. And through binoculars or a telescope, you'll see Venus's phase change dramatically during September - from nearly half phase to a larger thinner crescent!

Jupiter, Saturn and Mars continue their brilliant appearances this month. Look southwest after sunset.

Use the summer constellations help you trace the Milky Way.

Sagittarius: where stars and some brighter clumps appear as steam from the teapot.

Aquila: where the Eagle's bright Star Altair, combined with Cygnus's Deneb, and Lyra's Vega mark the Summer Triangle. 

Cassiopeia, the familiar "w"- shaped constellation completes the constellation trail through the Summer Milky Way. Binoculars will reveal double stars, clusters and nebulae. 

Between September 12th and the 20th, watch the Moon pass from near Venus, above Jupiter, to the left of Saturn and finally above Mars! 

Both Neptune and brighter Uranus can be spotted with some help from a telescope this month.

Look at about 1:00 a.m. local time or later in the southeastern sky. You can find Mercury just above Earth's eastern horizon shortly before sunrise. Use the Moon as your guide on September 7 and 8th.

And although there are no major meteor showers in September, cometary dust appears in another late summer sight, the morning Zodiacal light. Try looking for it in the east on moonless mornings very close to sunrise. To learn more about the Zodiacal light, watch "What's Up" from March 2018.

Watch the full What’s Up for September Video: 

There are so many sights to see in the sky. To stay informed, subscribe to our What’s Up video series on Facebook.

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What’s Up For August 2018?

The summer Perseids are here! 

The Perseid meteor shower is the best of the year! It peaks on a Moonless summer night from 4 p.m. EST on August 12 until 4 a.m. EST on August 13.

Because the new Moon falls near the peak night, the days before and after the peak will also provide nice, dark skies. Your best window of observation is from a few hours after twilight until dawn, on the days surrounding the peak.

Unlike most meteor showers, which have a short peak of high meteor rates, the Perseids have a very broad peak, as Earth takes more than three weeks to plow through the wide trail of cometary dust from comet Swift-Tuttle.

The Perseids appear to radiate from the constellation Perseus, visible in the northern sky soon after sunset this time of year. Observers in mid-northern latitudes will have the best views.

You should be able to see some meteors from July 17 to August 24, with the rates increasing during the weeks before August 12 and decreasing after August 13.

Observers should be able to see between 60 and 70 per hour at the peak. Remember, you don't have to look directly at the constellation to see them. You can look anywhere you want to-even directly overhead.

Meteor showers like the Perseids are caused by streams of meteoroids hitting Earth's atmosphere. The particles were once part of their parent comet-or, in some cases, from an asteroid.

The parade of planets Venus, Jupiter, Saturn and Mars--and the Milky Way continue to grace the evening sky, keeping you and the mosquitoes company while you hunt for meteors.

Watch the full What’s Up for August Video: 

There are so many sights to see in the sky. To stay informed, subscribe to our What’s Up video series on Facebook.

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What’s Up - July 2018

What's Up for July?

Mars is closest to Earth since 2003!

July’s night skies feature Mars opposition on the 27th, when Mars, Earth, and the Sun all line up, and Mars’ closest approach to Earth since 2003 on the 31st. 

If you've been sky watching for 15 years or more, then you'll remember August 2003, when Mars approached closer to Earth than it had for thousands of years.

It was a very small percentage closer, but not so much that it was as big as the moon as some claimed.   

Astronomy clubs everywhere had long lines of people looking through their telescopes at the red planet, and they will again this month!

 If you are new to stargazing, this month and next will be a great time to check out Mars. 

Through a telescope, you should be able to make out some of the light and dark features, and sometimes polar ice. Right now, though, a huge Martian dust storm is obscuring many features, and less planetary detail is visible.

July 27th is Mars opposition, when Mars, Earth, and the Sun all line up, with Earth directly in the middle.

A few days later on July 31st is Mars' closest approach. That's when Mars and Earth are nearest to each other in their orbits around the Sun. Although there will be a lot of news focusing on one or the other of these two dates, Mars will be visible for many months.

By the end of July, Mars will be visible at sunset.

But the best time to view it is several hours after sunset, when Mars will appear higher in the sky.

Mars will still be visible after July and August, but each month it will shrink in apparent size as it travels farther from Earth in its orbit around the Sun.

On July 27th a total lunar eclipse will be visible in Australia, Asia, Africa, Europe and South America.

For those viewers, Mars will be right next to the eclipsing moon!

Next month will feature August's summer Perseids. It's not too soon to plan a dark sky getaway for the most popular meteor shower of the year! 

Watch the full What’s Up for July Video:

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What’s Up - June 2018

What’s Up For June?

Jupiter and Venus at sunset, Mars, Saturn and Vesta until dawn.

First up is Venus. It reaches its highest sunset altitude for the year this month and sets more than two hours after sunset.

You can't miss Jupiter, only a month after its opposition--when Earth was directly between Jupiter and the Sun.

The best time to observe Jupiter through a telescope is 10:30 p.m. at the beginning of the month and as soon as it's dark by the end of the month.  

Just aim your binoculars at the bright planet for a view including the four Galilean moons. Or just enjoy Jupiter with your unaided eye!

Saturn is at opposition June 27th, when it and the Sun are on opposite sides of Earth. It rises at sunset and sets at sunrise. Great Saturn viewing will last several more months. The best views this month will be just after midnight.

All year, the rings have been tilted wide open--almost 26 degrees wide this month--giving us a great view of Saturn's distinctive rings.

The tilt offers us a view of the north polar region, so exquisitely imaged by the Cassini spacecraft.

Near Saturn, the brightest asteroid--Vesta--is so bright that it can be seen with your unaided eye. It will be visible for several months.

A detailed star chart will help you pick out the asteroid from the stars. The summer Milky way provides a glittery backdrop.

Finally, Mars grows dramatically in brightness and size this month and is visible by 10:30 p.m. by month end.

The best views are in the early morning hours. Earth's closest approach with Mars is only a month away. It's the closest Mars has been to us since 2003.

Watch the full What’s Up for June Video: 

There are so many sights to see in the sky. To stay informed, subscribe to our What’s Up video series on Facebook. Make sure to follow us on Tumblr for your regular dose of space: http://nasa.tumblr.com.  

What's Up? - May 2018

What’s Up For May?

The Moon and Saturn meet Mars in the morning as our InSight spacecraft launches to the Red Planet on May 5!

You won't want to miss red Mars in the southern morning skies this month.

InSight, our first mission to explore Mars' deep interior, launches on May 5th with a launch window that begins at 4:05 a.m. PDT and lasts for two hours.

Some lucky viewers in central and southern California and even parts of the Mexican Pacific coast will get a chance to see the spacecraft launch with their unaided eyes AND its destination, Mars, at the same time.

Mars shines a little brighter than last month, as it approaches opposition on July 27th. That's when Mars and the Sun will be on opposite sides of the Earth. This will be Mars' closest approach to Earth since 2003! 

Compare the planet's increases in brightness with your own eyes between now and July 27th. 

The Eta Aquarid meteor shower will be washed out by the Moon this month, but if you are awake for the InSight launch anyway, have a look. This shower is better viewed from the southern hemisphere, but medium rates of 10 to 30 meteors per hour MAY be seen before dawn.

Of course, you could travel to the South Pacific to see the shower at its best!

There's no sharp peak to this shower--just several nights with good rates, centered on May 6th. 

Jupiter reaches opposition on May 9th, heralding the best Jupiter-observing season, especially for mid-evening viewing. That's because the king of the planets rises at sunset and sets at dawn. 

Wait a few hours after sunset, when Jupiter is higher in the sky, for the best views. If you viewed Jupiter last month, expect the view to be even better this month!

Watch the full What’s Up for May Video: 

There are so many sights to see in the sky. To stay informed, subscribe to our What’s Up video series on Facebook. Make sure to follow us on Tumblr for your regular dose of space: http://nasa.tumblr.com.   

What’s Up - April 2018

What’s Up For April? 

The Moon, Mars and Saturn and the Lyrid meteor shower!

The Moon, Mars and Saturn

The Moon, Mars and Saturn form a pretty triangle in early April, the Lyrid Meteors are visible in late April, peaking high overhead on the 22nd.

You won't want to miss red Mars and golden Saturn in the south-southeast morning skies this month. Mars shines a little brighter than last month.

By the 7th, the Moon joins the pair. From a dark sky you may see some glow from the nearby Milky Way.

Lyrid Meteors

Midmonth, start looking for Lyrid meteors, which are active from April 14 through the 30th. They peak on the 22nd.

The Lyrids are one of the oldest known meteor showers and have been observed for 2,700 years. The first recorded sighting of a Lyrid meteor shower goes back to 687 BC by the Chinese. The pieces of space debris that interact with our atmosphere to create the Lyrids originate from comet C/1861 G1 Thatcher. Comet Thatcher was discovered on 5 April 1861 by A. E. Thatcher.

In the early morning sky, a patient observer will see up to more than a dozen meteors per hour in this medium-strength shower, with 18 meteors per hour calculated for the peak. U.S. observers should see good rates on the nights before and after this peak.

A bright first quarter moon plays havoc with sky conditions, marring most of the typically faint Lyrid meteors. But Lyra will be high overhead after the moon sets at midnight, so that's the best time to look for Lyrids.

Jupiter & Juno

Jupiter will also be visible in the night sky this month! 

Through a telescope, Jupiter's clouds belts and zones are easy to see. 

And watch the Great Red Spot transit--or cross--the visible (Earth-facing) disk of Jupiter every 8 hours.

Our Juno spacecraft continues to orbit this gas giant, too!

And Juno's JunoCam citizen science team is creating exciting images of Jupiter's features based on the latest spacecraft data.

Next month Jupiter is at opposition--when it rises at sunset, sets at sunrise, and offers great views for several months!

Watch the full What’s Up for April Video: 

There are so many sights to see in the sky. To stay informed, subscribe to our What’s Up video series on Facebook. Make sure to follow us on Tumblr for your regular dose of space: http://nasa.tumblr.com.   

Using the Power of Space to Fight Cancer

From cancer research to DNA sequencing, the International Space Space is proving to be an ideal platform for medical research. But new techniques in fighting cancer are not confined to research on the space station. Increasingly, artificial intelligence is helping to "read" large datasets. And for the past 15 years, these big data techniques pioneered by our Jet Propulsion Laboratory have been revolutionizing biomedical research.

Microgravity Research on Space Station

On Earth, scientists have devised several laboratory methods to mimic normal cellular behavior, but none of them work exactly the way the body does. Beginning more than 40 years ago aboard Skylab and continuing today aboard the space station, we and our partners have conducted research in the microgravity of space.  In this environment, in vitro cells arrange themselves into three-dimensional groupings, or aggregates. These aggregates more closely resemble what actually occurs in the human body. Cells in microgravity also tend to clump together more easily, and they experience reduced fluid shear stress -- a type of turbulence that can affect their behavior. The development of 3D structure and enhanced cell differentiation seen in microgravity may help scientists study cell behavior and cancer development in models that behave more like tissues in the human body.

In addition, using the distinctive microgravity environment aboard the station, researchers are making further advancements in cancer therapy. The process of microencapsulation was investigated aboard the space station in an effort to improve the Earth-based technology. Microencapsulation is a technique that creates tiny, liquid-filled, biodegradable micro-balloons that can serve as delivery systems for various compounds, including specific combinations of concentrated anti-tumor drugs. For decades, scientists and clinicians have looked for the best ways to deliver these micro-balloons, or microcapsules, directly to specific treatment sites within a cancer patient, a process that has the potential to revolutionize cancer treatment.

A team of scientists at Johnson Space Center used the station as a tool to advance an Earth-based microencapsulation system, known as the Microencapsulation Electrostatic Processing System-II (MEPS-II), as a way to make more effective microcapsules. The team leveraged fluid behavior in microgravity to develop a new technique for making these microcapsules that would be more effective on Earth. In space, microgravity brought together two liquids incapable of mixing on Earth (80 percent water and 20 percent oil) in such a way that spontaneously caused liquid-filled microcapsules to form as spherical, tiny, liquid-filled bubbles surrounded by a thin, semipermeable, outer membrane. After studying these microcapsules on Earth, the team was able to develop a system to make more of the space-like microcapsules on Earth and are now performing activities leading to FDA approval for use in cancer treatment.  

In addition, the ISS National Laboratory managed by the Center for the Advancement of Science in Space (CASIS) has also sponsored cancer-related investigations.  An example of that is an investigation conducted by the commercial company Eli Lilly that seeks to crystallize a human membrane protein involved in several types of cancer together with a compound that could serve as a drug to treat those cancers. 

"So many things change in 3-D, it's mind-blowing -- when you look at the function of the cell, how they present their proteins, how they activate genes, how they interact with other cells," said Jeanne Becker, Ph.D., a cell biologist at Nano3D Biosciences in Houston and principal investigator for a study called Cellular Biotechnology Operations Support Systems: Evaluation of Ovarian Tumor Cell Growth and Gene Expression, also known as the CBOSS-1-Ovarian study. "The variable that you are most looking at here is gravity, and you can't really take away gravity on Earth. You have to go where gravity is reduced." 

Crunching Big Data Using Space Knowledge

Our Jet Propulsion Laboratory often deals with measurements from a variety of sensors -- say, cameras and mass spectrometers that are on our spacecraft. Both can be used to study a star, planet or similar target object. But it takes special software to recognize that readings from very different instruments relate to one another.

There’s a similar problem in cancer research, where readings from different biomedical tests or instruments require correlation with one another. For that to happen, data have to be standardized, and algorithms must be “taught” to know what they’re looking for.

Because space exploration and cancer research share a similar challenge in that they both must analyze large datasets to find meaning, JPL and the National Cancer Institute renewed their research partnership to continue developing methods in data science that originated in space exploration and are now supporting new cancer discoveries.

JPL’s methods are leading to the development of a single, searchable network of cancer data that researcher can work into techniques for the early diagnosis of cancer or cancer risk. In the time they’ve worked together, the two organizations’ efforts have led to the discovery of six new Food and Drug Administration-approved cancer biomarkers. These agency-approved biomarkers have been used in more than 1 million patient diagnostic tests worldwide.

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