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Our Human Research Program is conducting a Twins Study on retired twin astronauts Scott and Mark Kelly. The study began during Scott Kelly’s One-Year Mission, which encompassed International Space Station Expeditions 43, 44, 45 and 46.
Now that Scott has returned from space, researchers are integrating data as well as taking measurements on Earth from the twins. This is the first time we have conducted Omics research on identical twins. Omics is a broad area of biological and molecular studies that, in general, means the study of the entire complement of biomolecules, like proteins; metabolites or genes.
Comparing various types of molecular information on identical individuals while one undergoes unique stresses, follows a defined diet, and resides in microgravity to one who resides on Earth, with gravity, should yield interesting results. It is hoped one day that all individuals will have access to having their Omics profiles done. This is a first step towards personalizing medicine for astronauts and hopefully for the rest of us.
For background, check out NASA’s Omics video series at https://www.nasa.gov/twins-study.
Kjell Lindgren, M.D., NASA astronaut, Expedition 44/45 Flight Engineer and medical officer
Susan M. Bailey, Ph.D., Twins Study Principal Investigator, Professor, Radiation Cancer Biology & Oncology, Department of Environmental and Radiological Health Sciences, College of Veterinary Medicine & Biomedical Sciences, Colorado State University
Christopher E. Mason, Ph.D., Twins Study Principal Investigator, WorldQuant Foundations Scholar, Affiliate Fellow of Genomics, Ethics, and Law, ISP, Yale Law School, Associate Professor, Department of Physiology and Biophysics, Weill Cornell Medicine
Brinda Rana, Ph.D., Associate Professor, Department of Psychiatry, University of California San Diego School of Medicine
Michael P. Snyder, Ph.D., M.D., FACS, Twins Study Principal Investigator, Stanford W. Ascherman, Professor in Genetics, Chair, Dept. of Genetics, Director, Center for Genomics and Personalized Medicine, Stanford School of Medicine
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