Microbes - Blog Posts

Science-Heavy SpaceX Dragon Headed to Space Station

Heads up: a new batch of science is headed to the International Space Station aboard the SpaceX Dragon on April 2, 2018. Launching from Florida's Cape Canaveral Air Force Station atop a Falcon 9 rocket, this fire breathing (well, kinda…) spacecraft will deliver science that studies thunderstorms on Earth, space gardening, potential pathogens in space, new ways to patch up wounds and more.

Let's break down some of that super cool science heading 250 miles above Earth to the orbiting laboratory:

Sprites and Elves in Space

Atmosphere-Space Interactions Monitor (ASIM) experiment will survey severe thunderstorms in Earth's atmosphere and upper-atmospheric lightning, or transient luminous events. 

These include sprites, flashes caused by electrical break-down in the mesosphere; the blue jet, a discharge from cloud tops upward into the stratosphere; and ELVES, concentric rings of emissions caused by an electromagnetic pulse in the ionosphere.

Here's a graphic showing the layers of the atmosphere for reference:

Metal Powder Fabrication

Our Sample Cartridge Assembly (MSL SCA-GEDS-German) experiment will determine underlying scientific principles for a fabrication process known as liquid phase sintering, in microgravity and Earth-gravity conditions.

Science term of the day: Liquid phase sintering works like building a sandcastle with just-wet-enough sand; heating a powder forms interparticle bonds and formation of a liquid phase accelerates this solidification, creating a rigid structure. But in microgravity, settling of powder grains does not occur and larger pores form, creating more porous and distorted samples than Earth-based sintering. 

Sintering has many applications on Earth, including metal cutting tools, automotive engine connecting rods, and self-lubricating bearings. It has potential as a way to perform in-space fabrication and repair, such as building structures on the moon or creating replacement parts during extraterrestrial exploration.

Plants in space! It's l[a]unch time!

Understanding how plants respond to microgravity and demonstrating reliable vegetable production in space represent important steps toward the goal of growing food for future long-duration missions. The Veggie Passive Orbital Nutrient Delivery System (Veggie PONDS) experiment will test a passive nutrient delivery system in the station's Veggie plant growth facility by cultivating lettuce and mizuna greens for harvest and consumption on orbit.

The PONDS design features low mass and low maintenance, requires no additional energy, and interfaces with the Veggie hardware, accommodating a variety of plant types and growth media.

Quick Science Tip: Download the Plant Growth App to grow your own veggies in space! Apple users can download the app HERE! Android users click HERE!

Testing Materials in Space

The Materials ISS Experiment Flight Facility (MISSE-FF) experiment will provide a unique platform for testing how materials, coatings and components react in the harsh environment of space.

A continuation of a previous experiment, this version's new design eliminates the need for astronauts to perform spacewalks for these investigations. New technology includes power and data collection options and the ability to take pictures of each sample on a monthly basis, or more often if required. The testing benefits a variety of industries, including automotive, aeronautics, energy, space, and transportation.

New Ways to Develop Drugs in Space

Microgravity affects movement and effectiveness of drugs in unique ways. Microgravity studies already have resulted in innovative medicines to treat cancer, for example. The Metabolic Tracking investigation determines the possibility of developing improved drugs in microgravity, using a new method to test the metabolic impacts of drug compounds. This could lead to more effective, less expensive drugs.

Follow @ISS_Research on Twitter for your daily dose of nerdy, spacey goodness.

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The As, Gs, Cs and Ts of the Space Station: First In-Space Microbe Identification

Being able to identify microbes in real-time aboard the International Space Station, without having to send them back to Earth for identification first, would be totally amazing for the world of microbiology and space exploration.

The Genes in Space 3 team turned that possibility into a reality this year, when it completed the first-ever sample-to-sequence process entirely aboard the space station.

The ability to identify microbes in space could aid in the ability to diagnose and treat astronauts in real time, as well as assisting in the identification of life on other planets. It could also benefit other experiments aboard the space station.

HELPFUL SCIENCE HINT: Identifying microbes involves isolating the DNA of samples, and then amplifying – or making lots and lots (and LOTS) of copies - of that DNA that can then be sequenced, or identified.  

As part of regular monitoring, petri plates were touched to various surfaces of the space station. NASA astronaut Peggy Whitson transferred cells from growing bacterial colonies on those plates into miniature test tubes, something that had never been done before in space (first OMG moment!).

Once the cells were successfully collected, it was time to isolate the DNA and prepare it for sequencing, enabling the identification of the unknown organisms – another first for space microbiology.

Enter Hurricane Harvey. *thunder booms*

“We started hearing the reports of Hurricane Harvey the week in between Peggy performing the first part of collecting the sample and gearing up for the actual sequencing,” said Sarah Wallace, the project’s primary investigator.

When our Johnson Space Center (JSC) in Houston became inaccessible due hurricane conditions, Marshall Space Flight Center’s Payload Operations Integration Center in Huntsville, Alabama worked to connect Wallace to Whitson using Wallace’s personal cell phone.

With a hurricane wreaking havoc outside, Wallace and Whitson set out to make history.

The data were downlinked to the team in Houston for analysis and identification.

“Once we actually got the data on the ground we were able to turn it around and start analyzing it,” said Aaron Burton, the project’s co-investigator. “You get all these squiggle plots and you have to turn that into As, Gs, Cs and Ts.”

Those As, Gs, Cs and Ts are more than just a nerdy alphabet – they are Adenine, Guanine, Cytosine and Thymine – the four bases that make up each strand of DNA and can tell you what organism the strand of DNA came from. 

“Right away, we saw one microorganism pop up, and then a second one, and they were things that we find all the time on the space station,” said Wallace. “The validation of these results would be when we got the sample back to test on Earth.”

Soon after, the samples returned to Earth aboard the Soyuz spacecraft, along with Whitson.

With the samples now in the team’s JSC lab, tests were completed in ground labs to confirm the findings from the space station. They ran the tests again and again, and then once more, to confirm accuracy. Each time, the results were exactly the same on the ground as in orbit. (second OMG moment!)

“We did it. Everything worked perfectly,” said Sarah Stahl, microbiologist.

This capability could change future space exploration.

“As a microbiologist,” said Wallace, “My goal is really so that when we go and we move beyond ISS and we’re headed towards Mars or the moon or wherever we are headed to, we have a process that the crew can have that great understanding of the environment, based on molecular technology.”

For more information, follow @ISS_Research. 

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